2. Gene
  3. Fxn - frataxin Gene

Fxn - frataxin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as FA; X25; FARR; Frda

Gene ID: 14297 | Gene type: protein coding

About Fxn

Summary

Predicted to enable several functions, including 2 iron, 2 sulfur cluster binding activity; ferroxidase activity; and iron ion binding activity. Acts upstream of or within several processes, including adult walking behavior; negative regulation of organ growth; and proprioception. Located in mitochondrion. Is expressed in several structures, including brain; cartilage condensation; heart; hemolymphoid system; and lower jaw incisor. Used to study Friedreich ataxia. Human ortholog(s) of this gene implicated in Friedreich ataxia; Friedreich ataxia 1; and type 2 diabetes mellitus. Orthologous to human FXN (frataxin). [provided by Alliance of Genome Resources, Apr 2022]

Fxn Products(1)

mRNA Protein Name
NM_008044.3 NP_032070.1 frataxin, mitochondrial precursor
Protein Preferred Names Protein Names

frataxin, mitochondrial

Friedreich ataxia

Recombinant Fxn Proteins

Cat. No. Product Name Accession Purity
HY-P71735 FXN Protein, Mouse (P.pastoris, His) O35943 (L78-T207) ≥95%
HY-P72199 FXN Protein, Mouse (His) O35943 (L78-T207) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05162 FXN Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-149737 FXn / Unkown
HY-158740 1(R)-(Trifluoromethyl)oleyl alcohol Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fxn NCBI NCBI:2395
Macaca fascicularis Fxn NCBI NCBI:102120656
Rattus norvegicus Fxn NCBI NCBI:499335