2. Gene
  3. CTBS - chitobiase Gene

CTBS - chitobiase Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CTB

Gene ID: 1486 | Gene type: protein coding

About CTBS

Cytogenetic location: 1p22.3 Genomic coordinates (GRCh38): 1:84,549,611-84,574,440 (from NCBI)

This gene has 4 transcripts (splice variants), 203 orthologues and 6 paralogues. Ubiquitous expression in prostate (RPKM 12.0), liver (RPKM 10.6) and 25 other tissues.

Summary

Chitobiase is a lysosomal glycosidase involved in degradation of asparagine-linked oligosaccharides on glycoproteins (Aronson and Kuranda, 1989 [PubMed 2531691]).[supplied by OMIM, Nov 2010]

CTBS Products(1)

mRNA Protein Name
NM_004388.3 NP_004379.1 di-N-acetylchitobiase precursor

CTBS Protein Structure

Glyco_hydro_18

Glyco_hydro_18: Glycosyl hydrolases family 18 (108 - 357)

  • 0
  • 100
  • 200
  • 300
  • 385 a.a.
Protein Preferred Names Protein Names

di-N-acetylchitobiase

chitobiase, di-N-acetyl-

Related Diseases

Diseases Alias
Mannosidosis, Beta A, Lysosomal

Beta-Mannosidosis

Lysosomal Beta-Mannosidase Deficiency

Beta-Mannosidase Deficiency

Beta-D-Mannosidosis

Mannosidosis, Beta

MANSB

Lysosomal Beta A Mannosidosis
Mannosidosis, Alpha B, Lysosomal

Alpha-Mannosidosis

Lysosomal Alpha-D-Mannosidase Deficiency

Deficiency Of Alpha-Mannosidase

Alpha-Mannosidase B Deficiency

Mannosidosis

MANSA

Mannosidosis, Alpha-, Types I And Ii

Alpha-D-Mannosidosis

Alpha-Mannosidase Deficiency

Α-Mannosidosis

Alpha Mannosidase B Deficiency

Mannosidosis, Alpha B Lysosomal

Lysosomal Alpha B Mannosidosis

Alpha-Mannosidosis, Infantile Form

Lysosomal Alpha-D-Mannosidase Deficiency, Infantile Form

Alpha-Mannosidosis, Adult Form

Lysosomal Alpha-D-Mannosidase Deficiency, Adult Form

Alpha-Mannosidosis Types I And Ii

Mannosidase Deficiency Diseases
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-134964 CTB 99.93% Phase 4
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99513 Zamerovimab / Phase 3
HY-P99727 Mazorelvimab Inhibitor / Phase 3
Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-D2254 CTB probe-1 / Unkown
HY-RS03285 CTBS Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CTBS VGNC VGNC:71540
Mus musculus CTBS MGD MGI:1921495
Felis catus CTBS VGNC VGNC:107519
Canis familiaris CTBS VGNC VGNC:39688
Bos taurus CTBS VGNC VGNC:27786
Rattus norvegicus CTBS RGD RGD:621338