2. Gene
  3. SRFBP1 - serum response factor binding protein 1 Gene

SRFBP1 - serum response factor binding protein 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as P49; Rlb1; BUD22; STRAP; p49/STRAP

Gene ID: 153443 | Gene type: protein coding

About SRFBP1

Cytogenetic location: 5q23.1 Genomic coordinates (GRCh38): 5:121,961,975-122,078,935 (from NCBI)

This gene has 2 transcripts (splice variants) and 196 orthologues. Ubiquitous expression in thyroid (RPKM 4.8), fat (RPKM 4.6) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to be located in perinuclear region of cytoplasm. Predicted to be part of 90S preribosome. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

SRFBP1 Products(1)

mRNA Protein Name
NM_152546.3 NP_689759.2 serum response factor-binding protein 1

SRFBP1 Protein Structure

BUD22

BUD22: BUD22 (369 - 428)

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  • 429 a.a.
Protein Preferred Names Protein Names

serum response factor-binding protein 1

BUD22 homolog

Recombinant SRFBP1 Proteins

Cat. No. Product Name Accession Purity
HY-P77215 SRFBP1 Protein, Human (sf9, His-GST) Q8NEF9 (M1-D429) ≥95%

Related Diseases

Diseases Alias
Aortic Aneurysm, Familial Thoracic 10

AAT10

Aortic Aneurysm, Thoracic, With Or Without Aortic Dissection

Aneurysm, Aortic, Thoracic, Familial, Type 10
Aortic Aneurysm, Familial Thoracic 1

Thoracic Aortic Aneurysm

Annuloaortic Ectasia

Familial Thoracic Aortic Aneurysm And Aortic Dissection

Familial Aortic Dissection

Familial Taad

Familial Thoracic Aortic Aneurysm

Congenital Aneurysm Of Ascending Aorta

Familial Aortic Aneurysm

Familial Thoracic Aortic Aneurysm And Dissection

Aortic Aneurysm, Thoracic

AAT1

Faa1

Aortic Dissection, Familial

Aortic Aneurysm, Familial Thoracic

Aneurysm, Thoracic Aortic

Faa

Ftaad

Taa

Taad

Cystic Medial Necrosis Of Aorta

Familial Non-Syndromic Thoracic Aortic Aneurysm And Aortic Dissection

Aortic Aneurysm Thoracic

Familial Aortic Aneurysms

Aneurysm, Aortic, Thoracic, Familial, Type 1

Aneurysm Of Thoracic Aorta

Intrathoracic Aneurysm

Thoracic Aorta Aneurysm

Thoracic Aortic Aneurysm Without Rupture

Thoracic Aneurysm

Thorax Arterial Aneurysm

Thoracic Artery Aneurysm

Thoracic Arterial Aneurysm

Thorax Aneurysm

Thorax Aortic Aneurysm

Dissection Of Thoracic Aorta
Cutis Laxa

Generalized Elastolysis

Loose Skin

Dermatolysis

Dermatomegaly

Cutis Laxa Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13761 SRFBP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta SRFBP1 VGNC VGNC:77996
Mus musculus SRFBP1 MGD MGI:1914472
Rattus norvegicus SRFBP1 RGD RGD:1359398
Canis familiaris SRFBP1 VGNC VGNC:46800
Felis catus SRFBP1 VGNC VGNC:102335
Bos taurus SRFBP1 VGNC VGNC:55312
Others SRFBP1 NCBI