2. Gene
  3. Hpn - hepsin Gene

Hpn - hepsin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Hlb320

Gene ID: 15451 | Gene type: protein coding

About Hpn

Summary

This gene encodes a type II transmembrane serine Protease that may function in diverse processes, including regulation of cell growth. Deficiency in this gene results in hearing loss. The protein is cleaved into a catalytic serine Protease chain and a non-catalytic scavenger receptor cysteine-rich chain, which associate via a single disulfide bond. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]

Hpn Products(3)

mRNA Protein Name
NM_001110252.2 NP_001103722.1 serine protease hepsin isoform 1 precursor
NM_001276269.1 NP_001263198.1 serine protease hepsin isoform 3 precursor
NM_008281.4 NP_032307.2 serine protease hepsin isoform 2 precursor
Protein Preferred Names Protein Names

serine protease hepsin

Recombinant Hpn Proteins

Cat. No. Product Name Accession Purity
HY-P77961 Hepsin/HPN Protein, Mouse (HEK293, His) O35453 (T60-P436) ≥95%

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B2087 Glycerol phenylbutyrate 99.81% Yes
Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-135366 HPN-01 Inhibitor 98.61% Phase 1
Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06342 HPN Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hpn NCBI NCBI:3249