2. Gene
  3. CAMSAP1 - calmodulin regulated spectrin associated protein 1 Gene

CAMSAP1 - calmodulin regulated spectrin associated protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 157922 | Gene type: protein coding

About CAMSAP1

Cytogenetic location: 9q34.3 Genomic coordinates (GRCh38): 9:135,808,487-135,907,546 (from NCBI)

This gene has 10 transcripts (splice variants), 280 orthologues and 2 paralogues. Broad expression in testis (RPKM 12.5), brain (RPKM 9.1) and 25 other tissues.

Summary

Enables microtubule minus-end binding activity and spectrin binding activity. Involved in several processes, including neuron projection development; regulation of cell morphogenesis; and regulation of microtubule polymerization. Located in microtubule. Colocalizes with microtubule minus-end. [provided by Alliance of Genome Resources, Apr 2022]

CAMSAP1 Products(2)

mRNA Protein Name
NM_001411031.1 NP_001397960.1 calmodulin-regulated spectrin-associated protein 1 isoform 3
NM_015447.4 NP_056262.3 calmodulin-regulated spectrin-associated protein 1 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables microtubule binding IDA
IDA: Inferred from direct assay
19508979 GOA
enables microtubule minus-end binding IDA
IDA: Inferred from direct assay
24486153 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables spectrin binding IDA
IDA: Inferred from direct assay
24117850 GOA
Biological Process GO Annotation Evidence Reference Source
involved in cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
21834987 GOA
involved in microtubule cytoskeleton organization IDA
IDA: Inferred from direct assay
24486153 GOA
involved in neuron projection development IGI
IGI: Inferred from genetic interaction
24117850 GOA
involved in neuron projection development IMP
IMP: Inferred from mutant phenotype
19508979 GOA
involved in regulation of cell morphogenesis IMP
IMP: Inferred from mutant phenotype
21834987 GOA
involved in regulation of microtubule polymerization IDA
IDA: Inferred from direct assay
24486153 GOA
Cellular Component GO Annotation Evidence Reference Source
located in microtubule IDA
IDA: Inferred from direct assay
19508979 GOA
colocalizes with microtubule minus-end IDA
IDA: Inferred from direct assay
24486153 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CAMSAP1 Protein Structure

CH

CH: Calponin homology (CH) domain (186 - 331)

CAMSAP_CKK

CAMSAP_CKK: Microtubule-binding calmodulin-regulated spectrin-associated (1463 - 1582)

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  • 1602 a.a.
Protein Preferred Names Protein Names

calmodulin-regulated spectrin-associated protein 1

epididymis secretory sperm binding protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01871 CAMSAP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CAMSAP1 VGNC VGNC:26730
Macaca mulatta CAMSAP1 VGNC VGNC:70583
Rattus norvegicus CAMSAP1 RGD RGD:1565022
Canis familiaris CAMSAP1 VGNC VGNC:38689
Felis catus CAMSAP1 VGNC VGNC:60341
Mus musculus CAMSAP1 MGD MGI:3036242