REM2 - RRAD and GEM like GTPase 2 Gene

Homo sapiens

Gene ID: 161253 | Gene type: protein coding

About REM2

Cytogenetic location: 14q11.2 Genomic coordinates (GRCh38): 14:22,883,222-22,887,678 (from NCBI)

This gene has 2 transcripts (splice variants), 251 orthologues and 35 paralogues. Broad expression in bone marrow (RPKM 2.3), spleen (RPKM 0.7) and 14 other tissues.

Summary

Predicted to enable GTP binding activity and Calcium Channel regulator activity. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

REM2 Products(1)

mRNA	Protein	Name
NM_173527.3	NP_775798.2	GTP-binding protein REM 2

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

REM2 Protein Structure

Ras

0
100
200
300
340 a.a.

Protein Preferred Names

Protein Names

GTP-binding protein REM 2

RAS (RAD and GEM)-like GTP binding 2

Related Diseases

Diseases

Alias

Long Qt Syndrome

Romano-Ward Syndrome	Long Q-T Syndrome
Lqt	Qt Syndrome, Long
Congenital Long Qt Syndrome	Familial Long Qt Syndrome

Long Qt Syndrome 2

LQT2	Long Qt Syndrome, Acquired, Reduced Susceptibility To
Long Qt Syndrome 1/2	Long Qt Syndrome 2/3
Long Qt Syndrome 2/5	Long Qt Syndrome 2, Acquired, Susceptibility To
Long Qt Syndrome, Acquired, Reduced	Long Qt Syndrome Type 2
Long Qt Syndrome 2/9	Lqt1/2
Lqt2/3	Lqt2/5
Lqt2/9	Susceptibility To Acquired Long Qt Syndrome 2
Long Qt Syndrome-2	Qt Syndrome, Long, Type 2
Long Qt Syndrome 1-2	Long Qt Syndrome 2-3
Long Qt Syndrome 2-5	Long Qt Syndrome 9

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11838	REM2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	REM2	MGD	MGI:2155260
Rattus norvegicus	REM2	RGD	RGD:69081
Canis familiaris	REM2	VGNC	VGNC:45473
Felis catus	REM2	VGNC	VGNC:64570
Macaca mulatta	REM2	VGNC	VGNC:82220
Bos taurus	REM2	VGNC	VGNC:33864
Macaca fascicularis	REM2	NCBI	NCBI:102133589
Others	REM2	NCBI

Name
Email *

	Sorry, but the email address you supplied was invalid.