Il10rb - interleukin 10 receptor, beta Gene

Also known as Crfb4; CRF2-4; Il10r2; D21S58h; IL-10R2; D16H21S58; 6620401D04Rik

About Il10rb

Summary

Enables interleukin-10 receptor activity. Predicted to be involved in cytokine-mediated signaling pathway; positive regulation of cellular respiration; and positive regulation of receptor signaling pathway via JAK-STAT. Predicted to act upstream of or within defense response to virus. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in hepatitis B and inflammatory bowel disease 25. Orthologous to human IL10RB (interleukin 10 receptor subunit beta). [provided by Alliance of Genome Resources, Apr 2022]