2. Gene
  3. F11r - F11 receptor Gene

F11r - F11 receptor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as JAM; Jcam; JAM-1; JAM-A; Jcam1; Ly106; ESTM33; 9130004G24

Gene ID: 16456 | Gene type: protein coding

About F11r

Summary

Predicted to enable PDZ domain binding activity; Integrin binding activity; and protein homodimerization activity. Involved in intestinal absorption; regulation of cytokine production; and regulation of membrane permeability. Acts upstream of or within cell adhesion and epithelial cell differentiation. Located in bicellular tight junction. Is expressed in several structures, including 4-8 cell stage embryo; alimentary system; respiratory system; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human F11R (F11 receptor). [provided by Alliance of Genome Resources, Apr 2022]

F11r Products(1)

mRNA Protein Name
NM_172647.2 NP_766235.1 junctional adhesion molecule A precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
11689568 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cell adhesion IDA
IDA: Inferred from direct assay
15494378 MGI
acts upstream of or within epithelial cell differentiation IDA
IDA: Inferred from direct assay
15494378 MGI
involved in intestinal absorption IMP
IMP: Inferred from mutant phenotype
23885123 MGI
involved in regulation of cytokine production IMP
IMP: Inferred from mutant phenotype
18514073 MGI
involved in regulation of membrane permeability IMP
IMP: Inferred from mutant phenotype
23885123 MGI
Cellular Component GO Annotation Evidence Reference Source
located in bicellular tight junction IMP
IMP: Inferred from mutant phenotype
15494378 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

junctional adhesion molecule A

BV11 antigen

F11 receptor/F11R

junction cell adhesion molecule A

junction cell adhesion molecule1

junctional adhesion molecule 1

Recombinant F11r Proteins

Cat. No. Product Name Accession Purity
HY-P73855 JAM-A/CD321 Protein, Mouse (HEK293, Fc) O88792 (K27-A242) ≥95%
HY-P78322 JAM-A/CD321 Protein, Mouse (HEK293, His) O88792 (K27-G238) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04626 F11R Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens F11r NCBI NCBI:50848
Rattus norvegicus F11r NCBI NCBI:116479