2. Gene
  3. F11r - F11 receptor Gene

F11r - F11 receptor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Jam1

Gene ID: 116479 | Gene type: protein coding

About F11r

Summary

Predicted to enable PDZ domain binding activity; Integrin binding activity; and protein homodimerization activity. Involved in cell differentiation; positive regulation of blood pressure; and response to radiation. Located in cytoplasmic vesicle and slit diaphragm. Biomarker of hypertension; peptic esophagitis; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human F11R (F11 receptor). [provided by Alliance of Genome Resources, Apr 2022]

F11r Products(2)

mRNA Protein Name
NM_053796.1 NP_446248.1 junctional adhesion molecule A precursor
NM_053796.1 NP_446248.1 junctional adhesion molecule A precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
16617054 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cell differentiation IEP
IEP: Inferred from expression pattern
18506084 RGD
involved in positive regulation of blood pressure IDA
IDA: Inferred from direct assay
17420334 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cell-cell junction IDA
IDA: Inferred from direct assay
18506084 RGD
located in slit diaphragm IDA
IDA: Inferred from direct assay
19478094 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

junctional adhesion molecule A

JAM-1

JAM-A

junctional adhesion molecule 1

Recombinant F11r Proteins

Cat. No. Product Name Accession Purity
HY-P73853 JAM-A/CD321 Protein, Rat (HEK293, His) Q9JHY1 (K27-G238) ≥95%
HY-P73854 JAM-A/CD321 Protein, Rat (HEK293, Fc) Q9JHY1 (K27-G238) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04626 F11R Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens F11r NCBI NCBI:50848
Mus musculus F11r NCBI NCBI:16456