2. Gene
  3. Klrc1 - killer cell lectin-like receptor subfamily C, member 1 Gene

Klrc1 - killer cell lectin-like receptor subfamily C, member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as NKG2A; NKG2B; CD159a

Gene ID: 16641 | Gene type: protein coding

About Klrc1

Summary

Predicted to enable MHC class I protein complex binding activity; MHC class Ib receptor activity; and protein antigen binding activity. Predicted to be involved in natural killer cell mediated immunity; positive regulation of natural killer cell degranulation; and stimulatory C-type lectin receptor signaling pathway. Located in external side of plasma membrane. Is expressed in liver. Orthologous to several human genes including KLRC1 (killer cell lectin like receptor C1) and KLRC2 (killer cell lectin like receptor C2). [provided by Alliance of Genome Resources, Apr 2022]

Klrc1 Products(3)

mRNA Protein Name
NM_001136068.2 NP_001129540.1 NKG2-A/NKG2-B type II integral membrane protein isoform 1
NM_001288664.1 NP_001275593.1 NKG2-A/NKG2-B type II integral membrane protein isoform 3
NM_010652.2 NP_034782.1 NKG2-A/NKG2-B type II integral membrane protein isoform 2
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
14707119 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NKG2-A/NKG2-B type II integral membrane protein

Cluster of Differentiation 159a

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07391 KLRC1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Klrc1 NCBI NCBI:3821
Macaca fascicularis Klrc1 NCBI
Macaca mulatta Klrc1 NCBI NCBI:574146