P2ry14 - purinergic receptor P2Y14 Gene

Rattus norvegicus

Also known as Gpr105

Gene ID: 171108 | Gene type: protein coding

About P2ry14

Primary_assembly 2: 143,372,697-143,413,141 reverse strand.mRatBN7.2:CM026975.1

This gene has 5 transcripts (splice variants), 195 orthologues, 6 paralogues and is associated with 1 phenotype. Biased expression in Adrenal (RPKM 48.6), Spleen (RPKM 23.5) and 9 other tissues.

Summary

Predicted to enable G protein-coupled purinergic nucleotide receptor activity. Involved in immune response. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Orthologous to human P2RY14 (purinergic receptor P2Y14). [provided by Alliance of Genome Resources, Apr 2022]

P2ry14 Products(1)

mRNA	Protein	Name
NM_133577.2	NP_598261.2	P2Y purinoceptor 14

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in immune response	IMP IMP: Inferred from mutant phenotype	9295203	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

P2ry14 Protein Structure

7tm_GPCRs

0
100
200
300
338 a.a.

Protein Preferred Names

Protein Names

P2Y purinoceptor 14

G protein-coupled receptor 105	G protein-coupled receptor VTR 15-20
P2Y14	UDP-glucose receptor
VTR 15-20	purinergic receptor P2Y, G-protein coupled, 14

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09925	P2RY14 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS09926	P2ry14 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS09927	P2ry14 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	P2ry14	NCBI	NCBI:9934

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