2. Gene
  3. Masp1 - mannan-binding lectin serine peptidase 1 Gene

Masp1 - mannan-binding lectin serine peptidase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CCPII; Crarf; Masp1/3

Gene ID: 17174 | Gene type: protein coding

About Masp1

Summary

Enables serine-type endopeptidase activity. Involved in complement activation, lectin pathway. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; liver; and spleen. Human ortholog(s) of this gene implicated in 3MC syndrome 1. Orthologous to human MASP1 (MBL associated serine protease 1). [provided by Alliance of Genome Resources, Apr 2022]

Masp1 Products(2)

mRNA Protein Name
NM_001359083.1 NP_001346012.1 mannan-binding lectin serine protease 1 isoform 1 precursor
NM_008555.3 NP_032581.2 mannan-binding lectin serine protease 1 isoform 2 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables serine-type endopeptidase activity IDA
IDA: Inferred from direct assay
18424734 MGI
Biological Process GO Annotation Evidence Reference Source
involved in complement activation, lectin pathway IMP
IMP: Inferred from mutant phenotype
18424734 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
18424734 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mannan-binding lectin serine protease 1

MASP-1

complement factor MASP-3

complement-activating component of Ra-reactive factor

mannose-binding lectin-associated serine protease 1

mannose-binding protein-associated serine protease

ra-reactive factor serine protease p100

raRF

serine proteas

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08159 MASP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Masp1 NCBI NCBI:5648
Macaca fascicularis Masp1 NCBI NCBI:101866962
Rattus norvegicus Masp1 NCBI NCBI:64023