2. Gene
  3. Masp2 - mannan-binding lectin serine peptidase 2 Gene

Masp2 - mannan-binding lectin serine peptidase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as MAp19; MASP-2

Gene ID: 17175 | Gene type: protein coding

About Masp2

Summary

Predicted to enable several functions, including calcium-dependent protein binding activity; complement component C4b binding activity; and serine-type endopeptidase activity. Acts upstream of or within complement activation, lectin pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including brain and liver. Orthologous to human MASP2 (MBL associated serine protease 2). [provided by Alliance of Genome Resources, Apr 2022]

Masp2 Products(2)

mRNA Protein Name
NM_001003893.2 NP_001003893.1 mannan-binding lectin serine protease 2 isoform 1 precursor
NM_010767.3 NP_034897.1 mannan-binding lectin serine protease 2 isoform 2 precursor
Protein Preferred Names Protein Names

mannan-binding lectin serine protease 2

MBL-associated serine protease 2

mannose-binding protein-associated serine protease 2

Recombinant Masp2 Proteins

Cat. No. Product Name Accession Purity
HY-P77800 MASP2 Protein, Mouse (His) Q91WP0 (T287-F685) ≥95%

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99376 Narsoplimab Inhibitor 95.00% Phase 3
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P0227 SHU 9119 99.95% Unkown
HY-E70390 C1s Enzyme Antagonist / Unkown
HY-RS08160 MASP2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Masp2 NCBI NCBI:10747
Macaca fascicularis Masp2 NCBI NCBI:102131322
Rattus norvegicus Masp2 NCBI NCBI:64459