2. Gene
  3. Masp2 - MBL associated serine protease 2 Gene

Masp2 - MBL associated serine protease 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as MAp19; MASP-2

Gene ID: 64459 | Gene type: protein coding

About Masp2

Summary

Enables serine-type endopeptidase activity. Predicted to be involved in complement activation, lectin pathway. Predicted to be active in extracellular space. Orthologous to human MASP2 (MBL associated serine Protease 2). [provided by Alliance of Genome Resources, Apr 2022]

Masp2 Products(1)

mRNA Protein Name
NM_172043.1 NP_742040.1 mannan-binding lectin serine protease 2 precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables peptidase activity IDA
IDA: Inferred from direct assay
15060079 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
15060079 RGD
enables serine-type endopeptidase activity IDA
IDA: Inferred from direct assay
15060079 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mannan-binding lectin serine protease 2

mannan-binding lectin serine peptidase 2

mannose binding lectin-associated serine protease-2

mannose-binding protein-associated serine protease 2

Recombinant Masp2 Proteins

Cat. No. Product Name Accession Purity
HY-P77801 MASP2 Protein, Rat (His) A2VCV7 (T287-F685) ≥95%
HY-P77802 MASP2 Protein, Rat (Biotinylated, His) A2VCV7 (T287-F685) ≥95%

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99376 Narsoplimab Inhibitor 95.00% Phase 3
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P0227 SHU 9119 99.95% Unkown
HY-E70390 C1s Enzyme Antagonist / Unkown
HY-RS08160 MASP2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Masp2 NCBI NCBI:10747
Macaca fascicularis Masp2 NCBI NCBI:102131322
Mus musculus Masp2 NCBI NCBI:17175