Slc3a2 - solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 Gene

Mus musculus

Also known as 4F2; Cd98; Ly10; Mdu1; 4F2HC; Ly-10; NACAE; Ly-m10; Mgp-2hc

Gene ID: 17254 | Gene type: protein coding

About Slc3a2

Summary

Predicted to enable amino acid transmembrane transporter activity and double-stranded RNA binding activity. Predicted to be involved in carboxylic acid transport and viral entry into host cell. Predicted to act upstream of or within response to exogenous dsRNA. Located in apical pole of neuron. Is active in synapse. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and spinal cord. Orthologous to human SLC3A2 (solute carrier family 3 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc3a2 Products(3)

mRNA	Protein	Name
NM_001161413.2	NP_001154885.1	4F2 cell-surface antigen heavy chain isoform a
NM_001410771.1	NP_001397700.1	4F2 cell-surface antigen heavy chain isoform b
NM_008577.5	NP_032603.3	4F2 cell-surface antigen heavy chain isoform b

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	9915839	MGI
enables protein homodimerization activity	IDA IDA: Inferred from direct assay	9915839	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in L-leucine transport	IDA IDA: Inferred from direct assay	9915839	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in apical pole of neuron	IDA IDA: Inferred from direct assay	16399997	MGI
located in neuronal cell body	IDA IDA: Inferred from direct assay	16399997	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	9915839	MGI
is active in synapse	EXP EXP: Inferred from Experiment	24534009	MGI
is active in synapse	IDA IDA: Inferred from direct assay	24534009	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

4F2 cell-surface antigen heavy chain

CD98 antigen	CD98 heavy chain
antigen identified by monoclonal antibodies 4F2	solute carrier family 3 member 2
type II transmembrane protein

Recombinant Slc3a2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P75367	CD98 Protein, Mouse (HEK293, His)	NP_001154885.1 (A139-A565)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13242	SLC3A2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc3a2	NCBI	NCBI:6520
Rattus norvegicus	Slc3a2	NCBI	NCBI:50567

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