Slc3a2 - solute carrier family 3 member 2 Gene

Rattus norvegicus

Also known as Mdu1

Gene ID: 50567 | Gene type: protein coding

About Slc3a2

Summary

Enables neutral amino acid transmembrane transporter activity. Involved in L-leucine import across plasma membrane. Located in apical plasma membrane and basal plasma membrane. Orthologous to human SLC3A2 (solute carrier family 3 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc3a2 Products(2)

mRNA	Protein	Name
NM_001271089.2	NP_001258018.1	4F2 cell-surface antigen heavy chain isoform 2
NM_019283.3	NP_062156.2	4F2 cell-surface antigen heavy chain isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables neutral L-amino acid transmembrane transporter activity	IDA IDA: Inferred from direct assay	9480885	RGD
enables neutral L-amino acid transmembrane transporter activity	IMP IMP: Inferred from mutant phenotype	9726963	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in L-histidine transport	IDA IDA: Inferred from direct assay	10049700	RGD
involved in L-leucine import across plasma membrane	IDA IDA: Inferred from direct assay	9480885	RGD
involved in L-leucine transport	IDA IDA: Inferred from direct assay	9726963	RGD
involved in cellular response to glucose starvation	IEP IEP: Inferred from expression pattern	22185814	RGD
involved in neutral amino acid transport	IMP IMP: Inferred from mutant phenotype	9726963	RGD
involved in phenylalanine transport	IDA IDA: Inferred from direct assay	10049700	RGD
involved in response to muscle activity	IEP IEP: Inferred from expression pattern	24016666	RGD
involved in tryptophan transport	IDA IDA: Inferred from direct assay	10049700	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in apical plasma membrane	IDA IDA: Inferred from direct assay	11095508	RGD
located in basal plasma membrane	IDA IDA: Inferred from direct assay	11095508	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

4F2 cell-surface antigen heavy chain

4F2hc	antigen identified by monoclonal antibodies 4F2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	solute carrier family 3 (amino acid transporter heavy chain), member 2

Recombinant Slc3a2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P75663	CD98 Protein, Rat (HEK293, Fc)	Q794F9 (A100-A527)	≥95%
HY-P75664	CD98 Protein, Rat (HEK293, His)	Q794F9 (A100-A527)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13242	SLC3A2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc3a2	NCBI	NCBI:6520
Mus musculus	Slc3a2	NCBI	NCBI:17254

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