P2ry1 - purinergic receptor P2Y, G-protein coupled 1 Gene

Mus musculus

Also known as P2Y1; P2y1r

Gene ID: 18441 | Gene type: protein coding

About P2ry1

Chromosome 3: 60,910,216-60,916,403 forward strand.GRCm39:CM000996.3

This gene has 3 transcripts (splice variants), 191 orthologues, 13 paralogues and is associated with 4 phenotypes. Ubiquitous expression in colon adult (RPKM 5.3), large intestine adult (RPKM 4.9) and 27 other tissues.

Summary

Predicted to enable several functions, including A1 Adenosine Receptor binding activity; G protein-coupled purinergic nucleotide receptor activity; and adenyl ribonucleotide binding activity. Acts upstream of or within cellular response to organic cyclic compound and positive regulation of ion transport. Located in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and liver and biliary system. Orthologous to human P2RY1 (purinergic receptor P2Y1). [provided by Alliance of Genome Resources, Apr 2022]

P2ry1 Products(2)

mRNA	Protein	Name
NM_008772.5	NP_032798.1	P2Y purinoceptor 1
NM_001282016.1	NP_001268945.1	P2Y purinoceptor 1

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within cellular response to organic cyclic compound	IDA IDA: Inferred from direct assay	23479225	MGI
acts upstream of establishment of localization in cell	IGI IGI: Inferred from genetic interaction	15914557	MGI
acts upstream of establishment of localization in cell	IMP IMP: Inferred from mutant phenotype	15914557	MGI
acts upstream of monoatomic ion transport	IGI IGI: Inferred from genetic interaction	15914557	MGI
acts upstream of monoatomic ion transport	IMP IMP: Inferred from mutant phenotype	15914557	MGI
acts upstream of or within positive regulation of monoatomic ion transport	IGI IGI: Inferred from genetic interaction	15914557	MGI
acts upstream of or within positive regulation of monoatomic ion transport	IMP IMP: Inferred from mutant phenotype	15914557	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in plasma membrane	IDA IDA: Inferred from direct assay	15670583	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

P2ry1 Protein Structure

7tmA_P2Y1

0
100
200
300
373 a.a.

Protein Preferred Names

Protein Names

P2Y purinoceptor 1

ADP receptor	ATP receptor
P2Y1 receptor

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09914	P2RY1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS09915	P2ry1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS09916	P2ry1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	P2ry1	NCBI	NCBI:5028

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