Prkcq - protein kinase C, theta Gene

Mus musculus

Also known as Pkcq; PKC-0; PKCtheta; PKC-theta; A130035A12Rik

Gene ID: 18761 | Gene type: protein coding

About Prkcq

Chromosome 2: 11,176,919-11,306,033 forward strand.GRCm39:CM000995.3

This gene has 6 transcripts (splice variants), 204 orthologues, 5 paralogues and is associated with 57 phenotypes. Biased expression in testis adult (RPKM 34.4), thymus adult (RPKM 13.) and 6 other tissues.

Summary

Enables protein kinase C activity. Involved in several processes, including positive regulation of NF-kappaB transcription factor activity; positive regulation of cytokine production; and regulation of cell-cell adhesion. Acts upstream of or within several processes, including positive regulation of T cell proliferation; positive regulation of interleukin-2 production; and protein phosphorylation. Located in cytoplasm and immunological synapse. Is expressed in several structures, including adipose tissue; genitourinary system; gut; limb; and nervous system. Used to study retinal detachment. Orthologous to human PRKCQ (protein kinase C theta). [provided by Alliance of Genome Resources, Apr 2022]

Prkcq Products(1)

mRNA	Protein	Name
NM_008859.2	NP_032885.1	protein kinase C theta type

Prkcq Protein Structure

C1_nPKC_theta-like_rpt1

C1_nPKC_theta-like_rpt2

STKc_nPKC_theta

0
200
400
600
707 a.a.

Protein Preferred Names

Protein Names

protein kinase C theta type

PKC theta

nPKC-theta

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11137	PRKCQ Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS11138	Prkcq Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS11139	Prkcq Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Prkcq	NCBI	NCBI:5588

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