2. Gene
  3. Plaur - plasminogen activator, urokinase receptor Gene

Plaur - plasminogen activator, urokinase receptor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cd87; uPAR; u-PAR

Gene ID: 18793 | Gene type: protein coding

About Plaur

Summary

Predicted to enable Enzyme binding activity; protein domain specific binding activity; and signaling receptor binding activity. Predicted to be involved in several processes, including negative regulation of apoptotic signaling pathway; positive regulation of epidermal growth factor receptor signaling pathway; and positive regulation of release of cytochrome c from mitochondria. Is integral component of plasma membrane. Is expressed in several structures, including decidua; early conceptus; and spleen. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Orthologous to human PLAUR (plasminogen activator, urokinase receptor). [provided by Alliance of Genome Resources, Apr 2022]

Plaur Products(1)

mRNA Protein Name
NM_011113.4 NP_035243.1 urokinase plasminogen activator surface receptor precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
19667118 MGI
Cellular Component GO Annotation Evidence Reference Source
located in plasma membrane IDA
IDA: Inferred from direct assay
19897580 MGI
part of serine-type endopeptidase complex IPI
IPI: Inferred from physical interaction
20133942 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

urokinase plasminogen activator surface receptor

urokinase plasminogen activator receptor

Recombinant Plaur Proteins

Cat. No. Product Name Accession Purity
HY-P77275 uPAR Protein, Mouse (HEK293, His-Fc) NP_035243.1 (L24-T297) ≥95%
HY-P77276 uPAR Protein, Mouse (HEK293, His) P35456 (M1-T297) ≥95%
HY-P700848 uPAR Protein, Mouse (Biotinylated, HEK293, His-Avi) P35456-1 (L24-G298) ≥95%
HY-P700849 uPAR Protein, Mouse (HEK293, His-Avi) P35456-1 (L24-G298) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10648 PLAUR Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plaur NCBI NCBI:5329
Macaca fascicularis Plaur NCBI NCBI:102139334
Rattus norvegicus Plaur NCBI NCBI:50692