2. Gene
  3. Reg1 - regenerating islet-derived 1 Gene

Reg1 - regenerating islet-derived 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as PSP; PTP

Gene ID: 19692 | Gene type: protein coding

About Reg1

Summary

Predicted to enable several functions, including growth factor activity; identical protein binding activity; and peptidoglycan binding activity. Involved in several processes, including pancreas regeneration; phosphatidylinositol 3-kinase signaling; and type B pancreatic cell differentiation. Acts upstream of or within with a positive effect on gene expression. Located in collagen-containing extracellular matrix. Is expressed in several structures, including esophagus; lung; and pancreas. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to several human genes including REG1A (regenerating family member 1 alpha). [provided by Alliance of Genome Resources, Apr 2022]

Reg1 Products(2)

mRNA Protein Name
NM_009042.2 NP_033068.1 lithostathine-1 precursor
NM_009042.2 NP_033068.1 lithostathine-1 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within positive effect gene expression IMP
IMP: Inferred from mutant phenotype
16405968 MGI
involved in pancreas regeneration IMP
IMP: Inferred from mutant phenotype
16405968 MGI
involved in phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: Inferred from mutant phenotype
16405968 MGI
involved in positive regulation of protein phosphorylation IMP
IMP: Inferred from mutant phenotype
16405968 MGI
involved in type B pancreatic cell differentiation IMP
IMP: Inferred from mutant phenotype
16405968 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lithostathine-1

REG 1

islet of Langerhans regenerating protein 1

pancreatic stone protein 1

pancreatic thread protein 1

regenerating protein 1

Recombinant Reg1 Proteins

Cat. No. Product Name Accession Purity
HY-P71462 Lithostathine-1/Reg1 Protein, Mouse (His-SUMO) P43137 (22Q-165G) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11818 REG1A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS11819 REG1B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca fascicularis Reg1 NCBI
Rattus norvegicus Reg1 NCBI
Macaca mulatta Reg1 NCBI