2. Gene
  3. MCEMP1 - mast cell expressed membrane protein 1 Gene

MCEMP1 - mast cell expressed membrane protein 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as C19orf59

Gene ID: 199675 | Gene type: protein coding

About MCEMP1

Cytogenetic location: 19p13.2 Genomic coordinates (GRCh38): 19:7,677,090-7,679,829 (from NCBI)

This gene has 3 transcripts (splice variants) and 78 orthologues. Biased expression in lung (RPKM 39.7), bone marrow (RPKM 28.1) and 1 other tissue.

Summary

This gene encodes a single-pass transmembrane protein. Based on its expression pattern, it is speculated to be involved in regulating mast cell differentiation or immune responses. [provided by RefSeq, Jul 2008]

MCEMP1 Products(1)

mRNA Protein Name
NM_174918.3 NP_777578.3 mast cell-expressed membrane protein 1
Protein Preferred Names Protein Names

mast cell-expressed membrane protein 1

epididymis secretory sperm binding protein

MCEMP1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
MCEMP1 Q8IX19 CMTM5 Homo sapiens Q96DZ9-2
Validated Y2H
32296183
Intra
MCEMP1 Q8IX19 JOSD2 Homo sapiens Q8TAC2
Anti Tag CoIP
33961781
Intra
MCEMP1 Q8IX19 JOSD2 Homo sapiens Q8TAC2
Anti Tag CoIP
28514442
Intra
MCEMP1 Q8IX19 ASGR2 Homo sapiens P07307-3
Y2H Array
32296183
Intra
MCEMP1 Q8IX19 ASGR2 Homo sapiens P07307-3
Y2H Prey Pooling
32296183
Intra
MCEMP1 Q8IX19 ZDHHC15 Homo sapiens Q96MV8
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant MCEMP1 Proteins

Cat. No. Product Name Accession Purity
HY-P77080 MCEMP1 Protein, Human (HEK293, Fc) Q8IX19-1 (K107-Q187) ≥95%

Related Diseases

Diseases Alias
Noonan Syndrome 3

NS3

Noonan Syndrome, Type 3
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08221 MCEMP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus MCEMP1 VGNC VGNC:97283
Macaca mulatta MCEMP1 VGNC VGNC:97790
Canis familiaris MCEMP1 VGNC VGNC:81277
Felis catus MCEMP1 VGNC VGNC:102634
Mus musculus MCEMP1 MGD MGI:1916439
Rattus norvegicus MCEMP1 RGD RGD:1565374
Others MCEMP1 NCBI