2. Gene
  3. S100a9 - S100 calcium binding protein A9 (calgranulin B) Gene

S100a9 - S100 calcium binding protein A9 (calgranulin B) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as p14; Cagb; GAGB; L1Ag; BEE22; MRP14; 60B8Ag

Gene ID: 20202 | Gene type: protein coding

About S100a9

Summary

Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity. Involved in peptidyl-cysteine S-nitrosylation; positive regulation of blood coagulation; and regulation of translation. Acts upstream of or within several processes, including actin Cytoskeleton reorganization; astrocyte development; and regulation of Integrin biosynthetic process. Predicted to be located in cell junction; cytosol; and nucleoplasm. Predicted to be active in cytoplasm; extracellular space; and nucleus. Is expressed in several structures, including jaw; liver; otic capsule; skeleton; and spleen red pulp. Human ortholog(s) of this gene implicated in myocarditis. Orthologous to human S100A9 (S100 calcium binding protein A9). [provided by Alliance of Genome Resources, Apr 2022]

S100a9 Products(4)

mRNA Protein Name
NM_001281852.1 NP_001268781.1 protein S100-A9
NM_009114.3 NP_033140.1 protein S100-A9
NM_001281852.1 NP_001268781.1 protein S100-A9
NM_009114.3 NP_033140.1 protein S100-A9
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within actin cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
12529407 MGI
acts upstream of or within astrocyte development IGI
IGI: Inferred from genetic interaction
22577135 MGI
acts upstream of or within leukocyte chemotaxis IMP
IMP: Inferred from mutant phenotype
12529407 MGI
acts upstream of peptide secretion IDA
IDA: Inferred from direct assay
18820689 MGI
acts upstream of peptide secretion IMP
IMP: Inferred from mutant phenotype
18820689 MGI
involved in peptidyl-cysteine S-nitrosylation IMP
IMP: Inferred from mutant phenotype
25417112 MGI
involved in positive regulation of blood coagulation IMP
IMP: Inferred from mutant phenotype
24691441 MGI
acts upstream of or within positive regulation of peptide secretion IDA
IDA: Inferred from direct assay
18820689 MGI
acts upstream of or within positive regulation of peptide secretion IMP
IMP: Inferred from mutant phenotype
18820689 MGI
acts upstream of or within regulation of integrin biosynthetic process IMP
IMP: Inferred from mutant phenotype
12529407 MGI
involved in regulation of translation IMP
IMP: Inferred from mutant phenotype
25417112 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in cornified envelope IDA
IDA: Inferred from direct assay
26644517 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein S100-A9

S100 calcium-binding protein A9

leukocyte L1 complex heavy chain

migration inhibitory factor-related protein 14

Recombinant S100a9 Proteins

Cat. No. Product Name Accession Purity
HY-P74583 S100A9 Protein, Mouse (His) P31725 (A2-K113) ≥95%

S100a9 Antibodies

Cat. No. Product Name Application Reactivity
HY-P82149 S100 alpha9 Antibody (YA1894) WB, IHC-F, IHC-P, ICC/IF Mouse

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-10528 Tasquinimod Modulator 99.94% Phase 3
HY-100442 Paquinimod Inhibitor 99.90% Phase 2
Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10528S Tasquinimod-d3 Modulator 99.34% Unkown
HY-100442S1 Paquinimod-d5-1 Inhibitor 98.19% Unkown
HY-RS12386 S100A9 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-100442S Paquinimod-d5 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens S100a9 NCBI NCBI:6280
Canis familiaris S100a9 NCBI NCBI:490463
Macaca fascicularis S100a9 NCBI NCBI:102122456