1. Gene
  2. S100b - S100 protein, beta polypeptide, neural Gene

S100b - S100 protein, beta polypeptide, neural Gene

Mus musculus

Also known as Bpb

Gene ID: 20203 | Gene type: protein coding

About S100b

Summary

Predicted to enable several functions, including RAGE receptor binding activity; S100 protein binding activity; and metal ion binding activity. Involved in learning or memory. Acts upstream of or within memory and regulation of neuronal synaptic plasticity. Located in cytoplasm; neuronal cell body; and nucleus. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; aspergillosis; and schizophrenia. Orthologous to human S100B (S100 calcium binding protein B). [provided by Alliance of Genome Resources, Apr 2022]

S100b Products(1)

mRNA Protein Name
NM_009115.3 NP_033141.1 protein S100-B
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in adaptive thermogenesis IDA
IDA: Inferred from direct assay
31043739 MGI
involved in learning or memory IMP
IMP: Inferred from mutant phenotype
11891290 MGI
acts upstream of or within memory IMP
IMP: Inferred from mutant phenotype
11891290 MGI
involved in neuron projection extension IDA
IDA: Inferred from direct assay
2592414 MGI
involved in positive regulation of neuron differentiation IDA
IDA: Inferred from direct assay
2592414 MGI
acts upstream of or within regulation of neuronal synaptic plasticity IMP
IMP: Inferred from mutant phenotype
11891290 MGI
involved in sympathetic neuron projection extension IDA
IDA: Inferred from direct assay
31043739 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
24582971 MGI
is active in extracellular region IDA
IDA: Inferred from direct assay
31043739 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
15248193 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15782413 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein S100-B

S-100 protein beta chain

S-100 protein subunit beta

S100 calcium-binding protein B

Recombinant S100b Proteins

Cat. No. Product Name Accession Purity
HY-P71276 S100B Protein, Mouse (His) P50114 (M1-E92) ≥95%

Orthologs Information

Species Symbol Source ID
Homo sapiens S100b NCBI NCBI:6285
Canis familiaris S100b NCBI NCBI:491615