2. Gene
  3. Ccl2 - chemokine (C-C motif) ligand 2 Gene

Ccl2 - chemokine (C-C motif) ligand 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as JE; HC11; MCAF; MCP1; MCP-1; Scya2; Sigje; SMC-CF

Gene ID: 20296 | Gene type: protein coding

About Ccl2

Summary

This gene is one of several cytokine genes clustered on chromosome 11. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and memory T cells but not for neutrophils. The human ortholog has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis. [provided by RefSeq, Sep 2015]

Ccl2 Products(1)

mRNA Protein Name
NM_011333.3 NP_035463.1 C-C motif chemokine 2 precursor
Protein Preferred Names Protein Names

C-C motif chemokine 2

monocyte chemoattractant protein 1

monocyte chemotactic protein 1

platelet-derived growth factor-inducible protein JE

small-inducible cytokine A2

Recombinant Ccl2 Proteins

Cat. No. Product Name Accession Purity
HY-P7235 MCP-1/CCL2 Protein, Mouse (HEK293) P10148 (Q24-R96) ≥95%
HY-P7764 MCP-1/CCL2 Protein, Mouse P10148 (Q24-R96) ≥95%
HY-P72757 MCP-1/CCL2 Protein, Mouse (HEK293, His) P10148 (Q24-N148) ≥95%
HY-P74758 MCP-1/CCL2 Protein, Mouse (sf9, His) Q5SVU3 (Q24-N148) ≥95%
HY-P76489 MCP-1/CCL2 Protein, Mouse (Biotinylated, sf9, His) Q5SVU3 (Q24-N148) ≥95%
HY-P700164AF Animal-Free MCP-1/CCL2 Protein, Mouse (His) P10148 (Q24-N148) ≥95%

Related Agents

Approval
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0673 Pirfenidone Inhibitor 99.98% Yes
HY-B1322A Amodiaquine 99.98% Unkown
HY-B1322 Amodiaquine dihydrochloride dihydrate 99.89% Unkown
HY-B1322B Amodiaquine dihydrochloride 99.89% Unkown
Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-B0498 Bindarit Inhibitor 99.53% Phase 3
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99188 Carlumab Inhibitor 97.77% Phase 2
HY-P99450 Avdoralimab Inhibitor 95.16% Phase 2
Pre-clinical Phase
Bioactive Molecules (16)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-120501 B022 Inhibitor 99.37% Unkown
HY-W007376 Indole-3-carboxaldehyde 99.96% Unkown
HY-115644 BMS-470539 dihydrochloride Agonist 99.95% Unkown
HY-120897 NS-3-008 hydrochloride Inhibitor 99.65% Unkown
HY-149202 UT-11 Inhibitor 99.62% Unkown
HY-B0673S Pirfenidone-d5 Inhibitor 99.48% Unkown
HY-116247 ST247 Agonist 99.88% Unkown
HY-108554 Q94 hydrochloride Antagonist / Unkown
HY-121896 DSHN Activator / Unkown
HY-144334 CHIKV-IN-3 Inhibitor / Unkown
HY-160552 244cis / Unkown
HY-163655 Glutaminyl Cyclase Inhibitor 6 Inhibitor / Unkown
HY-B1322AS1 Amodiaquine-d10 hydrochloride / Unkown
HY-RS02089 CCL2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W104821 Rosolic acid Activator / Unkown
HY-N3887 Evoxine / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccl2 NCBI NCBI:6347
Macaca fascicularis Ccl2 NCBI NCBI:102135739
Susscrofa domestica Ccl2 NCBI
Rattus norvegicus Ccl2 NCBI NCBI:24770
Macaca mulatta Ccl2 NCBI NCBI:574138