2. Gene
  3. SLC36A1 - solute carrier family 36 member 1 Gene

SLC36A1 - solute carrier family 36 member 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as Dct1; PAT1; LYAAT1; TRAMD3

Gene ID: 206358 | Gene type: protein coding

About SLC36A1

Cytogenetic location: 5q33.1 Genomic coordinates (GRCh38): 5:151,344,596-151,556,085 (from NCBI)

This gene has 11 transcripts (splice variants), 249 orthologues and 15 paralogues. Broad expression in duodenum (RPKM 7.4), small intestine (RPKM 6.6) and 20 other tissues.

Summary

This gene encodes a member of the eukaryote-specific amino acid/Auxin permease (AAAP) 1 transporter family. The encoded protein functions as a proton-dependent, small amino acid transporter. This gene is clustered with related family members on chromosome 5q33.1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

SLC36A1 Products(4)

mRNA Protein Name
NM_001308150.2 NP_001295079.1 proton-coupled amino acid transporter 1 isoform b
NM_001308151.2 NP_001295080.1 proton-coupled amino acid transporter 1 isoform c
NM_001349740.2 NP_001336669.1 proton-coupled amino acid transporter 1 isoform d
NM_078483.4 NP_510968.2 proton-coupled amino acid transporter 1 isoform a

SLC36A1 Protein Structure

Aa_trans

Aa_trans: Transmembrane amino acid transporter protein (46 - 454)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 476 a.a.
Protein Preferred Names Protein Names

proton-coupled amino acid transporter 1

lysosomal amino acid transporter 1

Related Diseases

Diseases Alias
Iminoglycinuria

Iminoglycinuria, Digenic

IG
Hyperglycinuria

Glycinuria With Or Without Oxalate Urolithiasis

Glycinuria With Or Without Oxalate Nephrolithiasis

Iminoglycinuria Type Ii

HG
Hartnup Disorder

Hartnup Disease

HND

Neutral 1 Amino Acid Transport Defect

Neutral Amino Acid Transport Defect

Deficiency Of Tryptophan Oxygenase

Hartnup'S Disease

Aminoaciduria, Hartnup Type

Disorder Of Neutral Amino Acid Transport
Digenic Disease
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N2368 Arecaidine Inhibitor 99.58% Unkown
HY-N2368A Arecaidine hydrochloride Inhibitor 98.00% Unkown
HY-N2368B Arecaidine hydrobromide Inhibitor / Unkown
HY-RS13210 SLC36A1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus SLC36A1 VGNC VGNC:102322
Canis familiaris SLC36A1 VGNC VGNC:46382
Macaca mulatta SLC36A1 VGNC VGNC:77509
Mus musculus SLC36A1 MGD MGI:2445299
Bos taurus SLC36A1 VGNC VGNC:34838
Rattus norvegicus SLC36A1 RGD RGD:619801