Sos2 - SOS Ras/Rho guanine nucleotide exchange factor 2 Gene

Mus musculus

Also known as SOS-2; mSOS-2

Gene ID: 20663 | Gene type: protein coding

About Sos2

Summary

Enables guanyl-nucleotide exchange factor activity. Acts upstream of or within several processes, including B cell homeostasis; regulation of T cell activation; and regulation of pro-B cell differentiation. Is expressed in several structures, including genitourinary system; hemolymphoid system gland; intestine; liver; and lung. Human ortholog(s) of this gene implicated in Noonan syndrome 9. Orthologous to human SOS2 (SOS Ras/Rho guanine nucleotide exchange factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Sos2 Products(1)

mRNA	Protein	Name
NM_001135559.1	NP_001129031.1	son of sevenless homolog 2

Protein Preferred Names

Protein Names

son of sevenless homolog 2

Sos2 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Sos2	Q02384	Grb2	Mus musculus	Q60631	Anti Bait CoIP	15953601
Intra	Sos2	Q02384	Abi1	Mus musculus	Q8CBW3	Y2H	11003655

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-168480	SOS2 ligand 1	Ligand	/	Unkown
HY-RS13577	SOS2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Sos2	NCBI	NCBI:6655

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