2. Gene
  3. Rnf43 - ring finger protein 43 Gene

Rnf43 - ring finger protein 43 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 4732452J19Rik

Gene ID: 207742 | Gene type: protein coding

About Rnf43

Summary

Predicted to enable Frizzled binding activity and ubiquitin protein Ligase activity. Involved in negative regulation of Wnt signaling pathway and stem cell proliferation. Predicted to be located in endoplasmic reticulum; nucleus; and plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in alimentary system; genitourinary system; and lung. Orthologous to human RNF43 (Ring Finger Protein 43). [provided by Alliance of Genome Resources, Apr 2022]

Rnf43 Products(2)

mRNA Protein Name
NM_001363437.1 NP_001350366.1 E3 ubiquitin-protein ligase RNF43 isoform 2
NM_172448.4 NP_766036.2 E3 ubiquitin-protein ligase RNF43 isoform 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
31073040 MGI
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
22895187 MGI
involved in stem cell proliferation IMP
IMP: Inferred from mutant phenotype
22895187 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase RNF43

RING-type E3 ubiquitin transferase RNF43

Recombinant Rnf43 Proteins

Cat. No. Product Name Accession Purity
HY-P78030 RNF43 Protein, Mouse (HEK293, Fc) Q5NCP0-1 (G24-Y197) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P10810 QPH-FR Inhibitor / Unkown
HY-RS12093 RNF43 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rnf43 NCBI NCBI:54894
Canis familiaris Rnf43 NCBI NCBI:491114