2. Gene
  3. Astl - astacin-like metalloendopeptidase (M12 family) Gene

Astl - astacin-like metalloendopeptidase (M12 family) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Sas1b; 7420700F21

Gene ID: 215095 | Gene type: protein coding

About Astl

Summary

Enables aspartic-type peptidase activity and glutamic-type peptidase activity. Involved in several processes, including negative regulation of binding activity of sperm to zona pellucida; positive regulation of protein processing; and prevention of polyspermy. Located in cortical granule and plasma membrane. Is expressed in early conceptus and oocyte. Orthologous to human ASTL (astacin like metalloendopeptidase). [provided by Alliance of Genome Resources, Apr 2022]

Astl Products(2)

mRNA Protein Name
NM_001291003.1 NP_001277932.1 astacin-like metalloendopeptidase isoform a precursor
NM_172539.3 NP_766127.1 astacin-like metalloendopeptidase isoform b
Protein Preferred Names Protein Names

astacin-like metalloendopeptidase

oocyte astacin

ovastacin

sperm acrosomal SLLP1

sperm acrosomal SLLP1-binding protein

Recombinant Astl Proteins

Cat. No. Product Name Accession Purity
HY-P77566 ASTL/SAS1B Protein, Mouse (His) Q6HA09-1 (A24-D435) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01111 ASTL Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Astl NCBI NCBI:431705