2. Gene
  3. Thbd - thrombomodulin Gene

Thbd - thrombomodulin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as TM; CD141

Gene ID: 21824 | Gene type: protein coding

About Thbd

Summary

Predicted to enable calcium ion binding activity and transmembrane signaling receptor activity. Acts upstream of or within female pregnancy. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; extraembryonic component; genitourinary system; lung; and skeleton. Used to study thrombophilia. Human ortholog(s) of this gene implicated in several diseases, including acute kidney failure; atypical hemolytic-uremic syndrome; cerebrovascular disease (multiple); rheumatoid arthritis; and thrombophilia (multiple). Orthologous to human THBD (thrombomodulin). [provided by Alliance of Genome Resources, Apr 2022]

Thbd Products(1)

mRNA Protein Name
NM_009378.3 NP_033404.1 thrombomodulin precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within embryo development IMP
IMP: Inferred from mutant phenotype
7846065 MGI
acts upstream of or within female pregnancy IMP
IMP: Inferred from mutant phenotype
7846065 MGI
Cellular Component GO Annotation Evidence Reference Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
19299737 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thrombomodulin

fetomodulin

snoRNA MBII-339

Recombinant Thbd Proteins

Cat. No. Product Name Accession Purity
HY-P72451 Thrombomodulin Protein, Mouse (HEK293, His) P15306 (L17-S517) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14478 THBD Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Thbd NCBI NCBI:7056
Rattus norvegicus Thbd NCBI NCBI:83580