Timp2 - tissue inhibitor of metalloproteinase 2 Gene

Mus musculus

Also known as Timp-2; D11Bwg1104e

Gene ID: 21858 | Gene type: protein coding

About Timp2

Summary

Enables Enzyme activator activity; Integrin binding activity; and metalloendopeptidase inhibitor activity. Acts upstream of or within several processes, including negative regulation of cell population proliferation; regulation of MAPK cascade; and regulation of neuron differentiation. Located in basement membrane and cell surface. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and skeletal system. Human ortholog(s) of this gene implicated in Moyamoya disease. Orthologous to human TIMP2 (TIMP metallopeptidase inhibitor 2). [provided by Alliance of Genome Resources, Apr 2022]

Timp2 Products(1)

mRNA	Protein	Name
NM_011594.3	NP_035724.2	metalloproteinase inhibitor 2 precursor

Protein Preferred Names

Protein Names

metalloproteinase inhibitor 2

tissue inhibitor of metalloproteinases 2

Recombinant Timp2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71137	TIMP-2 Protein, Mouse (HEK293, His)	P25785 (C27-P220)	≥95%
HY-P71137A	TIMP-2 Protein, Mouse (HEK293, C-His)	P25785 (C27-P220)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14539	TIMP2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Timp2	NCBI	NCBI:7077

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