2. Gene
  3. ARL5B - ADP ribosylation factor like GTPase 5B Gene

ARL5B - ADP ribosylation factor like GTPase 5B Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ARL8

Gene ID: 221079 | Gene type: protein coding

About ARL5B

Cytogenetic location: 10p12.31 Genomic coordinates (GRCh38): 10:18,659,431-18,681,639 (from NCBI)

This gene has 1 transcript (splice variant), 200 orthologues and 30 paralogues. Ubiquitous expression in adrenal (RPKM 13.8), gall bladder (RPKM 10.5) and 25 other tissues.

Summary

ARL5B (ARL8) belongs to a family of proteins that are structurally similar to ADP-ribosylation factors (ARFs; see MIM 103180). ARLs and ARFs are part of the Ras superfamily of regulatory GTPases.[supplied by OMIM, Nov 2010]

ARL5B Products(1)

mRNA Protein Name
NM_178815.5 NP_848930.1 ADP-ribosylation factor-like protein 5B

ARL5B Protein Structure

Arf

Arf: ADP-ribosylation factor family (5 - 175)

  • 0
  • 100
  • 179 a.a.
Protein Preferred Names Protein Names

ADP-ribosylation factor-like protein 5B

ADP-ribosylation factor-like 5B

Related Diseases

Diseases Alias
Hereditary Spastic Paraplegia

Familial Spastic Paraplegia

Hereditary Spastic Paraparesis

Strumpell-Lorrain Disease

Familial Spastic Paraparesis

Hsp

Spg

Strümpell-Lorrain Disease

Spastic Paraplegia, Hereditary

French Settlement Disease

Strumpell-Lorrain Syndrome

Fsp

Spastic Paraplegia, Familial

Spastic Paraplegia Hereditary

Spastic Paraplegia 3, Autosomal Dominant

Spastic Paraparesis

Hereditary Spastic Paralysis

Familial Spastic Paralysis

Hereditary Spastic Ataxia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00992 ARL5B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ARL5B VGNC VGNC:38116
Felis catus ARL5B VGNC VGNC:59925
Bos taurus ARL5B VGNC VGNC:26148
Macaca mulatta ARL5B VGNC VGNC:69886
Mus musculus ARL5B MGD MGI:1923119
Rattus norvegicus ARL5B RGD RGD:1305569