ZBTB12 - zinc finger and BTB domain containing 12 Gene

Homo sapiens

Also known as G10; Bat9; NG35; D6S59E; C6orf46

Gene ID: 221527 | Gene type: protein coding

About ZBTB12

This gene has 1 transcript (splice variant), 1 gene allele, 158 orthologues and 28 paralogues. Ubiquitous expression in ovary (RPKM 4.1), endometrium (RPKM 1.9) and 23 other tissues.

Summary

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ZBTB12 Products(1)

mRNA	Protein	Name
NM_181842.3	NP_862825.1	zinc finger and BTB domain-containing protein 12

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA
enables sequence-specific double-stranded DNA binding	IDA IDA: Inferred from direct assay	28473536	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZBTB12 Protein Structure

BTB

zf-C2H2

0
100
200
300
400
459 a.a.

Protein Preferred Names

Protein Names

zinc finger and BTB domain-containing protein 12

HLA-B-associated transcript 9

ZBTB12 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	ZBTB12	Q9Y330	ZBTB26	Homo sapiens	Q9HCK0	Y2H Array	32296183
Intra	ZBTB12	Q9Y330	ZBTB26	Homo sapiens	Q9HCK0	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Immune System Organ Benign Neoplasm

Thymus Lipoma

Thymolipoma

Testicular Infarct

Infarction Of Testis

Testicular Infarction

Malignant Ovarian Cyst

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15962	ZBTB12 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ZBTB12	RGD	RGD:1302958
Mus musculus	ZBTB12	MGD	MGI:88133
Felis catus	ZBTB12	VGNC	VGNC:67161
Macaca mulatta	ZBTB12	VGNC	VGNC:79174
Bos taurus	ZBTB12	VGNC	VGNC:37060
Canis familiaris	ZBTB12	VGNC	VGNC:48522

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