RBM24 - RNA binding motif protein 24 Gene

Homo sapiens

Also known as RNPC6; dJ259A10.1

Gene ID: 221662 | Gene type: protein coding

About RBM24

Cytogenetic location: 6p22.3 Genomic coordinates (GRCh38): 6:17,281,361-17,293,871 (from NCBI)

This gene has 8 transcripts (splice variants), 274 orthologues and 24 paralogues. Biased expression in heart (RPKM 42.8), endometrium (RPKM 14.9) and 4 other tissues.

Summary

Enables mRNA 3'-UTR AU-rich region binding activity; mRNA CDS binding activity; and sequence-specific mRNA binding activity. Involved in several processes, including negative regulation of cytoplasmic translation; positive regulation of cell differentiation; and regulation of mRNA metabolic process. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RBM24 Products(3)

mRNA	Protein	Name
NM_001143941.1	NP_001137413.1	RNA-binding protein 24 isoform 3
NM_001143942.2	NP_001137414.1	RNA-binding protein 24 isoform 1
NM_153020.2	NP_694565.1	RNA-binding protein 24 isoform 2

RBM24 Protein Structure

RRM_1

0
100
200
236 a.a.

Protein Preferred Names

Protein Names

RNA-binding protein 24

RNA-binding region (RNP1, RRM) containing 6

Related Diseases

Diseases

Alias

Dilated Cardiomyopathy

Familial Dilated Cardiomyopathy	Primary Dilated Cardiomyopathy
Idiopathic Dilated Cardiomyopathy	Congestive Cardiomyopathy
Idiopathic Dilation Cardiomyopathy	Primary Familial Dilated Cardiomyopathy
Cardiomyopathy, Dilated	DCM
Cardiomyopathy, Familial Dilated	Dilated Cardiomyopathy, Familial
Hypokinetic Dilated Cardiomyopathy, Familial	Familial Idiopathic Cardiomyopathy
Fdc	Cardiomyopathy, Familial Idiopathic
Idiopathic Cardiomegaly	Dilated Congestive Cardiomyopathy
Chronic Dilated Cardiomyopathy	Ccm - [Congestive Cardiomyopathy]
Cocm - [Congestive Cardiomyopathy]	Dcm - [Dilated Cardiomyopathy]
Dilated-Hypokinetic Cardiomyopathy	Congestive Idiopathic Cardiomyopathy
Primary Idiopathic Dilated Cardiomyopathy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11742	RBM24 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	RBM24	MGD	MGI:3610364
Rattus norvegicus	RBM24	RGD	RGD:1584029
Macaca mulatta	RBM24	VGNC	VGNC:83456
Bos taurus	RBM24	VGNC	VGNC:33793

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