2. Gene
  3. Vegfc - vascular endothelial growth factor C Gene

Vegfc - vascular endothelial growth factor C Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as VEGF-C

Gene ID: 22341 | Gene type: protein coding

About Vegfc

Summary

Enables vascular endothelial growth factor receptor 3 binding activity. Involved in several processes, including negative regulation of osteoblast differentiation; positive regulation of angiogenesis; and positive regulation of mesenchymal stem cell proliferation. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; positive regulation of lymphangiogenesis; and positive regulation of peptidyl-tyrosine phosphorylation. Located in extracellular space. Is expressed in several structures, including alimentary system mesentery; brain; cardiovascular system; embryo mesenchyme; and genitourinary system. Used to study hereditary lymphedema. Human ortholog(s) of this gene implicated in breast carcinoma and hereditary lymphedema ID. Orthologous to human VEGFC (vascular endothelial growth factor C). [provided by Alliance of Genome Resources, Apr 2022]

Vegfc Products(1)

mRNA Protein Name
NM_009506.2 NP_033532.1 vascular endothelial growth factor C precursor
Protein Preferred Names Protein Names

vascular endothelial growth factor C

VRP

flt4 ligand

flt4-L

vascular endothelial growth factor-related protein

Recombinant Vegfc Proteins

Cat. No. Product Name Accession Purity
HY-P74474 VEGF-CC Protein, Mouse/Rat (HEK293, His) P97953/NP_033532.1/O35757 (A108-R223) ≥95%
HY-P74475 VEGF-CC Protein, Mouse/Rat (HEK293, Fc) P97953 (A108-R223)/O35757(A108-R223) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N2187 Deoxyshikonin 99.96% Unkown
HY-RS15637 VEGFC Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9920A Ramucirumab (anti-VEGFR) Antagonist 99.36% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vegfc NCBI NCBI:7424
Rattus norvegicus Vegfc NCBI NCBI:114111