2. Gene
  3. Xk - X-linked Kx blood group Gene

Xk - X-linked Kx blood group Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Xkh; XRG1; 1810038K19Rik

Gene ID: 22439 | Gene type: protein coding

About Xk

Summary

Acts upstream of or within several processes, including cellular divalent inorganic cation homeostasis; regulation of axon diameter; and skeletal muscle fiber development. Is active in plasma membrane. Is expressed in genitourinary system; gonadal fat pad; gut; liver; and mammary gland. Human ortholog(s) of this gene implicated in McLeod syndrome and hematopoietic system disease. Orthologous to human XK (X-linked Kx blood group). [provided by Alliance of Genome Resources, Apr 2022]

Xk Products(1)

mRNA Protein Name
NM_023500.2 NP_075989.1 endoplasmic reticulum membrane adapter protein XK
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within intracellular calcium ion homeostasis IGI
IGI: Inferred from genetic interaction
23122227 MGI
acts upstream of or within intracellular magnesium ion homeostasis IGI
IGI: Inferred from genetic interaction
23122227 MGI
acts upstream of or within myelination IMP
IMP: Inferred from mutant phenotype
24405768 MGI
acts upstream of or within regulation of axon diameter IGI
IGI: Inferred from genetic interaction
24405768 MGI
acts upstream of or within regulation of cell size IGI
IGI: Inferred from genetic interaction
23122227 MGI
acts upstream of or within skeletal muscle fiber development IGI
IGI: Inferred from genetic interaction
24405768 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in plasma membrane IDA
IDA: Inferred from direct assay
25231987 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

endoplasmic reticulum membrane adapter protein XK

Kell blood group precursor (McLeod phenotype) homolog

McLeod syndrome gene homolog

XK homolog

XK-related protein 1

membrane transport protein XK

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B1915 Micronomicin Inhibitor 99.92% Unkown
Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-108307 Micronomicin sulfate Inhibitor ≥98.0% Unkown
HY-113799 Echinosporin / Unkown
HY-120679 XK469 / Unkown
HY-RS15878 XK Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Xk NCBI NCBI:7504
Macaca fascicularis Xk NCBI NCBI:102122017