2. Gene
  3. Cd226 - CD226 antigen Gene

Cd226 - CD226 antigen Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Pta1; DNAM1; DNAM-1; TLiSA1

Gene ID: 225825 | Gene type: protein coding

About Cd226

Summary

Predicted to enable Integrin binding activity and protein kinase binding activity. Acts upstream of or within positive regulation of interferon-gamma production and positive regulation of natural killer cell cytokine production. Located in external side of plasma membrane. Is expressed in embryo. Orthologous to human CD226 (CD226 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd226 Products(2)

mRNA Protein Name
NM_001039149.1 NP_001034238.1 CD226 antigen isoform b
NM_178687.2 NP_848802.2 CD226 antigen isoform a precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
15752754 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cytokine production IDA
IDA: Inferred from direct assay
15752754 MGI
acts upstream of natural killer cell cytokine production IMP
IMP: Inferred from mutant phenotype
24658051 MGI
acts upstream of or within positive regulation of natural killer cell cytokine production IMP
IMP: Inferred from mutant phenotype
24658051 MGI
acts upstream of or within positive regulation of type II interferon production IMP
IMP: Inferred from mutant phenotype
24658051 MGI
Cellular Component GO Annotation Evidence Reference Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
19648922 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CD226 antigen

platelet and T cell activation antigen 1

Cd226 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Cross
Cd226 Q8K4F0 PVR Homo sapiens P15151
SPR
30591568
Cross
Cd226 Q8K4F0 PVR Homo sapiens P15151
X-Ray Diffraction
30591568
Cross
Cd226 Q8K4F0 PVR Homo sapiens P15151
GMS
30591568
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant Cd226 Proteins

Cat. No. Product Name Accession Purity
HY-P72669 DNAM-1 Protein, Mouse (HEK293, His) Q8K4F0 (E19-P254) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02211 CD226 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd226 NCBI NCBI:10666
Macaca fascicularis Cd226 NCBI NCBI:102117316
Rattus norvegicus Cd226 NCBI NCBI:307199