2. Gene
  3. Atf6 - activating transcription factor 6 Gene

Atf6 - activating transcription factor 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as ESTM49; Atf6alpha; 9630036G24; 9130025P16Rik

Gene ID: 226641 | Gene type: protein coding

About Atf6

Chromosome 1: 170,532,243-170,695,340 reverse strand.GRCm39:CM000994.3

This gene has 2 transcripts (splice variants), 218 orthologues, 9 paralogues and is associated with 7 phenotypes. Ubiquitous expression in heart adult (RPKM 1.2), genital fat pad adult (RPKM 8.5) and 28 other tissues.

Summary

Predicted to enable several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; protein heterodimerization activity; and ubiquitin protein Ligase binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including embryo mesenchyme; eye; liver; long bone; and tooth. Human ortholog(s) of this gene implicated in achromatopsia 7. Orthologous to human ATF6 (activating transcription factor 6). [provided by Alliance of Genome Resources, Apr 2022]

Atf6 Products(1)

mRNA Protein Name
NM_001081304.1 NP_001074773.1 cyclic AMP-dependent transcription factor ATF-6 alpha

Atf6 Protein Structure

bZIP_ATF6

bZIP_ATF6: cd14700 (295 - 346)

  • 0
  • 200
  • 400
  • 600
  • 656 a.a.
Protein Preferred Names Protein Names

cyclic AMP-dependent transcription factor ATF-6 alpha

ATF6-alpha

activating transcription factor 6 alpha

cAMP-dependent transcription factor ATF-6 alpha

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-108434 Ceapin-A7 99.15% Unkown
HY-124293 AA147 Activator 99.89% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atf6 NCBI NCBI:22926