2. Gene
  3. ZC3H3 - zinc finger CCCH-type containing 3 Gene

ZC3H3 - zinc finger CCCH-type containing 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as SMICL; ZC3HDC3

Gene ID: 23144 | Gene type: protein coding

About ZC3H3

Cytogenetic location: 8q24.3 Genomic coordinates (GRCh38): 8:143,437,659-143,541,447 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele, 181 orthologues and 2 paralogues. Ubiquitous expression in bone marrow (RPKM 6.1), testis (RPKM 5.7) and 25 other tissues.

Summary

Predicted to enable SMAD binding activity. Involved in regulation of mRNA polyadenylation. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZC3H3 Products(1)

mRNA Protein Name
NM_015117.3 NP_055932.2 zinc finger CCCH domain-containing protein 3
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
16115198 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZC3H3 Protein Structure

zf-CCCH

zf-CCCH: Zinc finger C-x8-C-x5-C-x3-H type (and similar) (670 - 694)

zf-CCCH

zf-CCCH: Zinc finger C-x8-C-x5-C-x3-H type (and similar) (776 - 794)

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  • 800
  • 948 a.a.
Protein Preferred Names Protein Names

zinc finger CCCH domain-containing protein 3

smad-interacting CPSF-like factor

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15992 ZC3H3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ZC3H3 VGNC VGNC:37105
Canis familiaris ZC3H3 VGNC VGNC:48558
Macaca mulatta ZC3H3 VGNC VGNC:104507
Rattus norvegicus ZC3H3 RGD RGD:1307276
Felis catus ZC3H3 VGNC VGNC:67185
Mus musculus ZC3H3 MGD MGI:2663721