1. Gene
  2. CLUH - clustered mitochondria homolog Gene

CLUH - clustered mitochondria homolog Gene

Homo sapiens

Also known as CLU1

Gene ID: 23277 | Gene type: protein coding

About CLUH

Cytogenetic location: 17p13.3 Genomic coordinates (GRCh38): 17:2,689,387-2,712,020 (from NCBI)

This gene has 15 transcripts (splice variants) and 254 orthologues. Ubiquitous expression in kidney (RPKM 25.8), duodenum (RPKM 18.1) and 25 other tissues.

Summary

Enables mRNA binding activity. Involved in intracellular distribution of mitochondria. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

CLUH Products(3)

mRNA Protein Name
NM_001366661.1 NP_001353590.1 clustered mitochondria protein homolog isoform 1
NM_001366662.1 NP_001353591.1 clustered mitochondria protein homolog isoform 3
NM_015229.4 NP_056044.4 clustered mitochondria protein homolog isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables mRNA binding IDA
IDA: Inferred from direct assay
25349259 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
Biological Process GO Annotation Evidence Reference Source
involved in intracellular distribution of mitochondria IMP
IMP: Inferred from mutant phenotype
25349259 GOA
involved in mitochondrion organization IMP
IMP: Inferred from mutant phenotype
25349259 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
25349259 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CLUH Protein Structure

CLU_N

CLU_N: Mitochondrial function, CLU-N-term (64 - 139)

CLU

CLU: Clustered mitochondria (356 - 577)

eIF3_p135

eIF3_p135: Translation initiation factor eIF3 subunit 135 (764 - 949)

TPR_10

TPR_10: Tetratricopeptide repeat (1019 - 1060)

TPR_12

TPR_12: Tetratricopeptide repeat (1100 - 1177)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1309 a.a.
Protein Preferred Names Protein Names

clustered mitochondria protein homolog

clustered mitochondria (cluA/CLU1) homolog

Related Diseases

Diseases Alias
Fish Allergy

Allergy To Fish

Dyschromatosis Universalis Hereditaria

Duh

Atrophic Rhinitis

Rhinitis, Atrophic

Ozena

Rhinitis Sicca

Dry Rhinitis

Ozaena

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Felis catus CLUH VGNC VGNC:60988
Rattus norvegicus CLUH RGD RGD:1307222
Bos taurus CLUH VGNC VGNC:50138
Canis familiaris CLUH VGNC VGNC:54935
Macaca mulatta CLUH VGNC VGNC:71370
Mus musculus CLUH MGD MGI:1921398