KIF13B - kinesin family member 13B Gene

Homo sapiens

Also known as GAKIN

Gene ID: 23303 | Gene type: protein coding

About KIF13B

Cytogenetic location: 8p12 Genomic coordinates (GRCh38): 8:29,067,278-29,263,388 (from NCBI)

This gene has 6 transcripts (splice variants), 277 orthologues and 41 paralogues. Ubiquitous expression in kidney (RPKM 15.2), colon (RPKM 14.6) and 25 other tissues.

Summary

Enables 14-3-3 protein binding activity and protein kinase binding activity. Involved in regulation of axonogenesis. Located in axon and cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

KIF13B Products(1)

mRNA	Protein	Name
NM_015254.4	NP_056069.2	kinesin-like protein KIF13B

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables 14-3-3 protein binding	IDA IDA: Inferred from direct assay	20194617	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	10859302	GOA
enables protein kinase binding	IPI IPI: Inferred from physical interaction	10859302	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in regulation of axonogenesis	IDA IDA: Inferred from direct assay	20194617	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in axon	IDA IDA: Inferred from direct assay	20194617	GOA
located in cytoplasm	IDA IDA: Inferred from direct assay	10859302	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

KIF13B Protein Structure

Kinesin

FHA

KIF1B

DUF3694

CAP_GLY

0
300
600
900
1200
1500
1826 a.a.

Protein Preferred Names

Protein Names

kinesin-like protein KIF13B

guanylate kinase associated kinesin

Related Diseases

Diseases

Alias

Deafness, Autosomal Recessive 84a

DFNB84A	Deafness, Autosomal Recessive 84
Autosomal Recessive Nonsyndromic Deafness 84a	Dfnb84
Deafness, Autosomal Recessive 84a, With Vestibular Dysfunction	Autosomal Recessive Deafness 84a
Autosomal Recessive Deafness 84a With Vestibular Dysfunction	Deafness, Autosomal Recessive, 84a
Deafness Autosomal Recessive 84	Deafness Autosomal Recessive 84a With Vestibular Dysfunction
Non-Syndromic Neurosensory Deafness Autosomal Recessive Type 84	Deafness, Autosomal Recessive, Type 84a

Meester-Loeys Syndrome

MRLS

Congenital Fibrosis Of The Extraocular Muscles

Congenital Fibrosis Of Extraocular Muscles	Cfeom
Feom	Congenital External Ophthalmoplegia
Congenital Fibrosis Syndrome	General Fibrosis Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07260	KIF13B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	KIF13B	VGNC	VGNC:42382
Bos taurus	KIF13B	VGNC	VGNC:30582
Mus musculus	KIF13B	MGD	MGI:1098265
Macaca mulatta	KIF13B	VGNC	VGNC:99471
Rattus norvegicus	KIF13B	RGD	RGD:1303307
Felis catus	KIF13B	VGNC	VGNC:82484

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