2. Gene
  3. FKBP15 - FKBP prolyl isomerase family member 15 Gene

FKBP15 - FKBP prolyl isomerase family member 15 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as FKBP133; PPP1R76; KIAA0674

Gene ID: 23307 | Gene type: protein coding

About FKBP15

Cytogenetic location: 9q32 Genomic coordinates (GRCh38): 9:113,161,006-113,221,277 (from NCBI)

This gene has 23 transcripts (splice variants), 210 orthologues, 18 paralogues and is associated with 1 phenotype. Ubiquitous expression in spleen (RPKM 13.2), appendix (RPKM 13.2) and 25 other tissues.

Summary

Predicted to enable actin binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in endocytosis and protein peptidyl-prolyl isomerization. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

FKBP15 Products(1)

mRNA Protein Name
NM_015258.2 NP_056073.1 FK506-binding protein 15
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
20923837 GOA
Cellular Component GO Annotation Evidence Reference Source
located in membrane IDA
IDA: Inferred from direct assay
22070227 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FKBP15 Protein Structure

FKBP_C

FKBP_C: FKBP-type peptidyl-prolyl cis-trans isomerase (193 - 286)

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  • 1219 a.a.
Protein Preferred Names Protein Names

FK506-binding protein 15

133 kDa FK506-binding protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04959 FKBP15 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus FKBP15 MGD MGI:2444782
Macaca mulatta FKBP15 VGNC VGNC:72557
Bos taurus FKBP15 VGNC VGNC:29020
Rattus norvegicus FKBP15 RGD RGD:1304816
Felis catus FKBP15 VGNC VGNC:62279
Canis familiaris FKBP15 VGNC VGNC:40888