2. Gene
  3. HAUS5 - HAUS augmin like complex subunit 5 Gene

HAUS5 - HAUS augmin like complex subunit 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as dgt5; KIAA0841

Gene ID: 23354 | Gene type: protein coding

About HAUS5

Cytogenetic location: 19q13.12 Genomic coordinates (GRCh38): 19:35,612,735-35,625,355 (from NCBI)

This gene has 9 transcripts (splice variants) and 93 orthologues. Ubiquitous expression in testis (RPKM 4.9), lymph node (RPKM 4.6) and 25 other tissues.

Summary

HAUS5 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]

HAUS5 Products(1)

mRNA Protein Name
NM_015302.2 NP_056117.1 HAUS augmin-like complex subunit 5
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
19369198 GOA
Biological Process GO Annotation Evidence Reference Source
involved in centrosome cycle IMP
IMP: Inferred from mutant phenotype
19427217 GOA
involved in spindle assembly IMP
IMP: Inferred from mutant phenotype
19369198 GOA
Cellular Component GO Annotation Evidence Reference Source
part of HAUS complex IDA
IDA: Inferred from direct assay
19369198 GOA
part of HAUS complex IPI
IPI: Inferred from physical interaction
20360068 GOA
located in centrosome IDA
IDA: Inferred from direct assay
21399614 GOA
located in mitotic spindle microtubule IDA
IDA: Inferred from direct assay
30723163 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HAUS5 Protein Structure

HAUS5

HAUS5: HAUS augmin-like complex subunit 5 (5 - 620)

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  • 633 a.a.
Protein Preferred Names Protein Names

HAUS augmin-like complex subunit 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06017 HAUS5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta HAUS5 VGNC VGNC:73256
Canis familiaris HAUS5 VGNC VGNC:41605
Bos taurus HAUS5 VGNC VGNC:29760
Mus musculus HAUS5 MGD MGI:1919159
Felis catus HAUS5 VGNC VGNC:62757
Rattus norvegicus HAUS5 RGD RGD:2318093