2. Gene
  3. ANGPTL2 - angiopoietin like 2 Gene

ANGPTL2 - angiopoietin like 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ARP2; HARP

Gene ID: 23452 | Gene type: protein coding

About ANGPTL2

Cytogenetic location: 9q33.3 Genomic coordinates (GRCh38): 9:127,087,348-127,122,635 (from NCBI)

This gene has 4 transcripts (splice variants), 128 orthologues and 25 paralogues. Broad expression in fat (RPKM 35.2), gall bladder (RPKM 19.9) and 22 other tissues.

Summary

Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and Angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the Angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action. [provided by RefSeq, Jul 2008]

ANGPTL2 Products(1)

mRNA Protein Name
NM_012098.3 NP_036230.1 angiopoietin-related protein 2 precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
22660330 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ANGPTL2 Protein Structure

Fibrinogen_C

Fibrinogen_C: Fibrinogen beta and gamma chains, C-terminal globular domain (276 - 487)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 493 a.a.
Protein Preferred Names Protein Names

angiopoietin-related protein 2

angiopoietin-like protein 2

Recombinant ANGPTL2 Proteins

Cat. No. Product Name Accession Purity
HY-P71652 ANGPTL2/Angiopoietin-like 2 Protein, Human (His-SUMO) Q9UKU9 (23Q-493H) ≥95%
HY-P75577 ANGPTL2/Angiopoietin-like 2 Protein, Human (HEK293, His) Q9UKU9-1 (D245-H493) ≥95%
HY-P78060 ANGPTL2/Angiopoietin-like 2 Protein, Human (Biotinylated, HEK293, His-Avi) Q9UKU9 (T260-H493) ≥95%
HY-P78380 ANGPTL2/Angiopoietin-like 2 Protein, Human (HEK293, His-Avi) Q9UKU9 (T260-H493) ≥95%

Related Diseases

Diseases Alias
Myositis Ossificans

Myisitis Ossificans

Ossification - Muscle
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00691 ANGPTL2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ANGPTL2 MGD MGI:1347002
Macaca mulatta ANGPTL2 VGNC VGNC:69814
Canis familiaris ANGPTL2 VGNC VGNC:37858
Bos taurus ANGPTL2 VGNC VGNC:25891
Rattus norvegicus ANGPTL2 RGD RGD:620004
Felis catus ANGPTL2 VGNC VGNC:67567
Others ANGPTL2 NCBI