2. Gene
  3. Pdk3 - pyruvate dehydrogenase kinase, isoenzyme 3 Gene

Pdk3 - pyruvate dehydrogenase kinase, isoenzyme 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 2610001M10Rik

Gene ID: 236900 | Gene type: protein coding

About Pdk3

Summary

Predicted to enable ATP binding activity; protein serine/threonine kinase activity; and pyruvate dehydrogenase (acetyl-transferring) kinase activity. Predicted to be involved in several processes, including hypoxia-inducible factor-1alpha signaling pathway; peroxisome proliferator activated receptor signaling pathway; and regulation of acetyl-CoA biosynthetic process from pyruvate. Predicted to act upstream of or within glucose metabolic process and phosphorylation. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease X-linked dominant 6. Orthologous to human PDK3 (pyruvate dehydrogenase kinase 3). [provided by Alliance of Genome Resources, Apr 2022]

Pdk3 Products(1)

mRNA Protein Name
NM_145630.3 NP_663605.1 pyruvate dehydrogenase kinase, isozyme 3
Protein Preferred Names Protein Names

pyruvate dehydrogenase kinase, isozyme 3

[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial

[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial

Recombinant Pdk3 Proteins

Cat. No. Product Name Accession Purity
HY-P71614 PDK3 Protein, Mouse (His) Q922H2 (I131-S362) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-121744 PS10 Inhibitor 99.01% Unkown
HY-12492 VER-246608 Inhibitor 99.10% Unkown
HY-19564 JX06 99.78% Unkown
HY-N6769 Radicicol Inhibitor 99.63% Unkown
HY-RS10277 PDK3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdk3 NCBI NCBI:5165