2. Gene
  3. Kel - Kell blood group Gene

Kel - Kell blood group Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ece3; CD238

Gene ID: 23925 | Gene type: protein coding

About Kel

Summary

Enables metallopeptidase activity. Acts upstream of or within several processes, including cellular divalent inorganic cation homeostasis; regulation of axon diameter; and skeletal muscle fiber development. Located in membrane. Orthologous to human KEL (Kell metallo-endopeptidase (Kell blood group)). [provided by Alliance of Genome Resources, Apr 2022]

Kel Products(2)

mRNA Protein Name
NM_032540.3 NP_115929.3 kell blood group glycoprotein homolog
NM_032540.3 NP_115929.3 kell blood group glycoprotein homolog
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables metallopeptidase activity IMP
IMP: Inferred from mutant phenotype
19544475 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of establishment of localization in cell IGI
IGI: Inferred from genetic interaction
19544475 MGI
acts upstream of or within intracellular calcium ion homeostasis IGI
IGI: Inferred from genetic interaction
23122227 MGI
acts upstream of or within intracellular magnesium ion homeostasis IGI
IGI: Inferred from genetic interaction
23122227 MGI
acts upstream of or within myelination IMP
IMP: Inferred from mutant phenotype
24405768 MGI
acts upstream of or within negative regulation of potassium ion transmembrane transport IGI
IGI: Inferred from genetic interaction
19544475 MGI
acts upstream of potassium ion transmembrane transport IGI
IGI: Inferred from genetic interaction
19544475 MGI
acts upstream of or within regulation of axon diameter IGI
IGI: Inferred from genetic interaction
24405768 MGI
acts upstream of or within regulation of cell size IGI
IGI: Inferred from genetic interaction
23122227 MGI
acts upstream of or within skeletal muscle fiber development IGI
IGI: Inferred from genetic interaction
24405768 MGI
Cellular Component GO Annotation Evidence Reference Source
located in membrane IDA
IDA: Inferred from direct assay
19544475 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kell blood group glycoprotein homolog

Kel blood group protein

Kell blood group, metallo-endopeptidase

Kell protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (10)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-139039 BSJ-4-116 Inhibitor 98.73% Unkown
HY-145765 JQAD1 98.24% Unkown
HY-123919 TL13-112 Inhibitor 98.15% Unkown
HY-122582 TL13-12 Inhibitor 98.06% Unkown
HY-155962 Tubulin polymerization-IN-47 Inhibitor 99.51% Unkown
HY-155963 Tubulin polymerization-IN-48 Inhibitor / Unkown
HY-158062 LC-1-40 / Unkown
HY-168439 HLB-0532259 Degrader / Unkown
HY-RS07233 KEL Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19110 Kel Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kel NCBI NCBI:3792
Macaca fascicularis Kel NCBI NCBI:102119961