2. Gene
  3. Agt - angiotensinogen Gene

Agt - angiotensinogen Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Ang; PAT; ANRT; AngII

Gene ID: 24179 | Gene type: protein coding

About Agt

Summary

Enables hormone activity. Involved in several processes, including MAPK cascade; regulation of ion transport; and regulation of secretion. Located in cytoplasm and extracellular space. Used to study several diseases, including artery disease (multiple); diabetic retinopathy; gastric ulcer; impotence; and sciatic neuropathy. Biomarker of several diseases, including cerebrovascular disease (multiple); glomerulonephritis (multiple); liver cirrhosis (multiple); lung disease (multiple); and prediabetes syndrome. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Henoch-Schoenlein purpura; artery disease (multiple); heart conduction disease (multiple); and hydronephrosis. Orthologous to human AGT (Angiotensinogen). [provided by Alliance of Genome Resources, Apr 2022]

Agt Products(1)

mRNA Protein Name
NM_134432.2 NP_602308.1 angiotensinogen precursor
Protein Preferred Names Protein Names

angiotensinogen

angiotensin II

angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

serpin A8

Recombinant Agt Proteins

Cat. No. Product Name Accession Purity
HY-P73651 Serpin A8/Angiotensinogen Protein, Rat (HEK293, His) P01015 (D25-V477) ≥95%

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-108764 Mipomersen sodium Inhibitor 97.50% Unkown
Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-W002585 O6-Benzylguanine 99.84% Phase 3
HY-143230 Custirsen / Phase 3
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99530 Valanafusp alfa / Phase 2
Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-150736 ODN 20844 Inhibitor / Unkown
HY-148413 Aprinocarsen sodium Inhibitor 90.35% Unkown
HY-150744 ODN 24888 Inhibitor / Unkown
HY-150215 ODN 105870 Inhibitor / Unkown
HY-150216 ODN 105871 Inhibitor / Unkown
HY-150740 ODN 21595 Inhibitor / Unkown
HY-P5939 Angiotensinogen (1-13) (human) / Unkown
HY-RS00466 AGT Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Agt NCBI NCBI:183
Mus musculus Agt NCBI NCBI:11606