2. Gene
  3. Ncam1 - neural cell adhesion molecule 1 Gene

Ncam1 - neural cell adhesion molecule 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Cd56; Ncam; N-CAM; NCAMC; NCAM-1; NCAM-C; N-CAM-1

Gene ID: 24586 | Gene type: protein coding

About Ncam1

Summary

Enables LRR domain binding activity and Phosphatase binding activity. Involved in several processes, including axon development; positive regulation of cardiac muscle cell proliferation; and thalamus development. Located in neuronal cell body and plasma membrane. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is integral component of postsynaptic membrane and integral component of presynaptic membrane. Used to study middle cerebral artery infarction. Biomarker of Alzheimer's disease; congestive heart failure; hypothyroidism; mental depression; and myocardial infarction. Human ortholog(s) of this gene implicated in bipolar disorder; middle cerebral artery infarction; and pancreatic Cancer. Orthologous to human NCAM1 (neural cell adhesion molecule 1). [provided by Alliance of Genome Resources, Apr 2022]

Ncam1 Products(5)

mRNA Protein Name
NM_001395707.1 NP_001382636.1 neural cell adhesion molecule 1 isoform 1 precursor
NM_001395708.1 NP_001382637.1 neural cell adhesion molecule 1 isoform 2 precursor
NM_001395709.1 NP_001382638.1 neural cell adhesion molecule 1 isoform 3 precursor
NM_001395710.1 NP_001382639.1 neural cell adhesion molecule 1 isoform 4 precursor
NM_031521.3 NP_113709.1 neural cell adhesion molecule 1 isoform 5 precursor
Protein Preferred Names Protein Names

neural cell adhesion molecule 1

Recombinant Ncam1 Proteins

Cat. No. Product Name Accession Purity
HY-P73749 NCAM-1/CD56 Protein, Rat (HEK293, His) P13596 (L20-T721) ≥95%

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99372 Lorvotuzumab 99.77% Phase 2
Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09063 NCAM1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ncam1 NCBI NCBI:4684
Macaca fascicularis Ncam1 NCBI NCBI:102144192
Mus musculus Ncam1 NCBI NCBI:17967