Slc5a2 - solute carrier family 5 (sodium/glucose cotransporter), member 2 Gene

Mus musculus

Also known as Sglt2

Gene ID: 246787 | Gene type: protein coding

About Slc5a2

Chromosome 7: 127,864,829-127,871,602 forward strand.GRCm39:CM001000.3

This gene has 12 transcripts (splice variants), 200 orthologues, 13 paralogues and is associated with 37 phenotypes. Biased expression in kidney adult (RPKM 372.3) and adrenal adult (RPKM 11.1).

Summary

Predicted to enable D-glucose transmembrane transporter activity; alpha-glucoside transmembrane transporter activity; and glucose:sodium symporter activity. Predicted to be involved in several processes, including alpha-glucoside transport; import across plasma membrane; and renal potassium excretion. Predicted to act upstream of or within carbohydrate transport and ion transport. Predicted to be located in brush border membrane. Predicted to be active in plasma membrane. Predicted to be integral component of membrane. Is expressed in urinary system. Human ortholog(s) of this gene implicated in renal glycosuria. Orthologous to human SLC5A2 (solute carrier family 5 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc5a2 Products(1)

mRNA	Protein	Name
NM_133254.5	NP_573517.1	sodium/glucose cotransporter 2

Slc5a2 Protein Structure

SLC5-6-like_sbd

0
200
400
600
670 a.a.

Protein Preferred Names

Protein Names

sodium/glucose cotransporter 2

Na(+)/glucose cotransporter 2

low affinity sodium-dependent glucose cotransporter

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13286	SLC5A2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS13287	Slc5a2 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS13288	Slc5a2 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc5a2	NCBI	NCBI:6524

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