2. Gene
  3. Tk1 - thymidine kinase 1 Gene

Tk1 - thymidine kinase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Tk

Gene ID: 24834 | Gene type: protein coding

About Tk1

Summary

Enables identical protein binding activity. Involved in several processes, including fetal process involved in parturition; response to cortisol; and thymidine metabolic process. Predicted to be located in cytoplasm. Orthologous to human TK1 (thymidine kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Tk1 Products(1)

mRNA Protein Name
NM_052800.1 NP_434687.1 thymidine kinase, cytosolic
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
23351158 RGD
Biological Process GO Annotation Evidence Reference Source
involved in digestive tract development IEP
IEP: Inferred from expression pattern
6701043 RGD
involved in fetal process involved in parturition IEP
IEP: Inferred from expression pattern
7208144 RGD
involved in liver development IEP
IEP: Inferred from expression pattern
995499 RGD
involved in response to copper ion IEP
IEP: Inferred from expression pattern
6642140 RGD
involved in response to cortisol IEP
IEP: Inferred from expression pattern
7208144 RGD
involved in response to nutrient levels IEP
IEP: Inferred from expression pattern
6701043 RGD
involved in response to toxic substance IEP
IEP: Inferred from expression pattern
6642140 RGD
involved in skeletal muscle cell proliferation IEP
IEP: Inferred from expression pattern
15748706 RGD
involved in thymidine metabolic process IDA
IDA: Inferred from direct assay
6642140 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thymidine kinase, cytosolic

thymidine kinase 1, soluble

Tk1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Tk1 P27158 Tk1 Rattus norvegicus P27158
GMS
23351158
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-107025 Cf1743 / Unkown
HY-RS14556 TK1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tk1 NCBI NCBI:7083
Canis familiaris Tk1 NCBI NCBI:100855947
Macaca fascicularis Tk1 NCBI NCBI:102119923
Mus musculus Tk1 NCBI NCBI:21877