2. Gene
  3. St6gal1 - ST6 beta-galactoside alpha-2,6-sialyltransferase 1 Gene

St6gal1 - ST6 beta-galactoside alpha-2,6-sialyltransferase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Siat1

Gene ID: 25197 | Gene type: protein coding

About St6gal1

Summary

Enables Sialyltransferase activity. Involved in several processes, including negative regulation of macrophage apoptotic process; protein sialylation; and regulation of substrate adhesion-dependent cell spreading. Located in Golgi medial cisterna; Golgi trans cisterna; and endoplasmic reticulum. Used to study high grade glioma. Orthologous to human ST6GAL1 (ST6 beta-galactoside alpha-2,6-sialyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

St6gal1 Products(2)

mRNA Protein Name
NM_001113344.1 NP_001106815.1 beta-galactoside alpha-2,6-sialyltransferase 1 isoform 1
NM_147205.2 NP_671738.2 beta-galactoside alpha-2,6-sialyltransferase 1 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables sialyltransferase activity IDA
IDA: Inferred from direct assay
12626411 RGD
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of chemotaxis IDA
IDA: Inferred from direct assay
11559557 RGD
involved in negative regulation of macrophage apoptotic process IDA
IDA: Inferred from direct assay
21930713 RGD
involved in positive regulation of mononuclear cell proliferation IDA
IDA: Inferred from direct assay
21930713 RGD
involved in protein sialylation IDA
IDA: Inferred from direct assay
21930713 RGD
involved in regulation of substrate adhesion-dependent cell spreading IDA
IDA: Inferred from direct assay
11559557 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
9046376 RGD
Cellular Component GO Annotation Evidence Reference Source
located in Golgi medial cisterna IDA
IDA: Inferred from direct assay
12626411 RGD
located in Golgi trans cisterna IDA
IDA: Inferred from direct assay
12626411 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

beta-galactoside alpha-2,6-sialyltransferase 1

CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1

ST6 beta-galactosamide alpha-2,6-sialyltranferase 1

ST6Gal I

ST6GalI

Sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase)

Sialyltransferase 1 (beta-galactoside alph

Recombinant St6gal1 Proteins

Cat. No. Product Name Accession Purity
HY-P76663 ST6GAL1 Protein, Rat (HEK293, His) P13721-1/NP_001106815.1 (K27-C403) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13852 ST6GAL1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens St6gal1 NCBI NCBI:6480
Mus musculus St6gal1 NCBI NCBI:20440